Release of platelet Met-enkephalin, but not serotonin, in migraine. A platelet response unique to migraine patients?
Plasma-induced release of platelet-serotonin and Met-enkephalin was studied by incubating platelets from migraineurs, tension headache patients and healthy volunteers with water, plasma collected during migraine attacks and with plasma collected during attack-free periods. Migraine-attack plasma, bu...
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Published in: | Journal of the neurological sciences Vol. 93; no. 1; p. 51 |
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Main Authors: | , , , , |
Format: | Journal Article |
Language: | English |
Published: |
Netherlands
01-10-1989
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Subjects: | |
Online Access: | Get more information |
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Summary: | Plasma-induced release of platelet-serotonin and Met-enkephalin was studied by incubating platelets from migraineurs, tension headache patients and healthy volunteers with water, plasma collected during migraine attacks and with plasma collected during attack-free periods. Migraine-attack plasma, but not migraine attack-free plasma, released Met-enkephalin from platelets of migraineurs. Platelets of healthy controls or tension headache sufferers did not release their Met-enkephalin in response to either incubation medium. In contrast to Met-enkephalin, serotonin was not released from platelets in relevant quantities by migraine-attack plasma. |
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ISSN: | 0022-510X |
DOI: | 10.1016/0022-510X(89)90160-3 |