Chronic ulcerative stomatitis associated with stratified epithelial specific antinuclear antibodies. A case report of a newly described disease entity

• Published in: Oral surgery, oral medicine, oral pathology Vol. 73; no. 5; p. 579
• Main Authors: Church, Jr, L F, Schosser, R H
• Format: Journal Article
• Language: English
• Published: United States 01-05-1992
• Subjects: Aged; Antibodies, Antinuclear - analysis; Chronic Disease; Dexamethasone - therapeutic use; Diagnosis, Differential; Epithelium - immunology; Female; Fluorescent Antibody Technique; Gingivitis, Necrotizing Ulcerative - diagnosis; Gingivitis, Necrotizing Ulcerative - drug therapy; Gingivitis, Necrotizing Ulcerative - immunology; Humans; Lichen Planus - diagnosis; Mouth Mucosa - immunology
• ISSN: 0030-4220
• DOI: 10.1016/0030-4220(92)90102-V

A case of erosive oral lesions associated with an unusual direct and indirect immunofluorescent pattern is presented. Rather than a submucosal band or intramucosal intercellular deposition, the pattern is that of an antinuclear antibody that reacts only with stratified epithelium. The clinical similarity of this case to erosive lichen planus is discussed. The usefulness of direct and indirect immunofluorescence techniques in the diagnosis of erosive oral lesions is stressed.