Screening for biologically active metabolites with endosymbiotic bacilli isolated from arthropods

Screening for biologically active metabolites with endosymbiotic bacilli isolated from arthropods

Endosymbiotic bacteria from the genus Bacillus were isolated from different compartments of the gut of various members of insects (Hexapoda) and millipedes (Diplopoda). They were grown in submerged culture and investigated by biological assays and HPLC-diode array analysis regarding their production...

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Bibliographic Details
Published in:FEMS microbiology letters Vol. 217; no. 2; pp. 199 - 205
Main Authors: Gebhardt, Klaus, Schimana, Judith, Müller, Johannes, Fiedler, Hans-Peter, Kallenborn, Helmut G, Holzenkämpfer, Meike, Krastel, Philipp, Zeeck, Axel, Vater, Joachim, Höltzel, Alexandra, Schmid, Dietmar G, Rheinheimer, Joachim, Dettner, Konrad
Format: Journal Article
Language:English
Published: Elsevier B.V 17-12-2002
Subjects:
Antibiotic
Arthropod
Bacillus
Endosymbiosis
Arthropod
Antibiotic
Endosymbiosis
Bacillus
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Summary:Endosymbiotic bacteria from the genus Bacillus were isolated from different compartments of the gut of various members of insects (Hexapoda) and millipedes (Diplopoda). They were grown in submerged culture and investigated by biological assays and HPLC-diode array analysis regarding their production of bioactive metabolites, which were isolated and determined in structure. Known compounds and yet unknown derivatives from the primary metabolism were detected, as well as antibacterially and antifungally acting peptide antibiotics.
ISSN:0378-1097
1574-6968
DOI:10.1016/S0378-1097(02)01065-0