Evaluation of anti-aging and antioxidant properties of a new rose variety, Ever-rose

• Published in: Chemical and biological technologies in agriculture Vol. 11; no. 1; pp. 119 - 17
• Main Authors: Han, Se Jik, Belousova, Polina, Kwon, Sangwoo, Jang, Jihui, Lee, Jun Bae, Kim, Hyunjae, You, Gayeon, Song, Jihyeon, Mok, Hyejung, Ha, Ho Su, Bae, So Jeong, Ha, In Jin, Lee, Min Young, Kim, Kyung Sook
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 22-08-2024; Springer Nature B.V; SpringerOpen
• Subjects: Aging; Aging (artificial); Agriculture; Anti-aging; Antioxidant; Antioxidants; Atomic force microscopy; Atomic force microscopy (AFM); Atomic properties; Biomedical and Life Sciences; Cell size; Cellular elasticity; Chemical composition; Elasticity; Flavonoids; High performance liquid chromatography; Interstitial collagenase; Irradiation; Life Sciences; Liquid chromatography; Mass spectrometry; Mass Spectrometry for Plant Applications; Mass spectroscopy; Matrix metalloproteinase; Matrix metalloproteinases; Metalloproteinase; Natural resources; Organic Chemistry; Plant Biochemistry; Plant Physiology; Proteolysis; Reactive oxygen species; Rose extracts; Scavenging; Scientific imaging; Soil Science & Conservation; Superoxide dismutase; Ultraviolet radiation; Variation; Xanthine oxidase; Rose extracts; Atomic force microscopy (AFM); Anti-aging; Antioxidant; Cellular elasticity
• ISSN: 2196-5641
• DOI: 10.1186/s40538-024-00653-2

Background
Rose flowers contain active ingredients such as flavonoids and volatile oils and are acknowledged to be good natural resources owing to their anti-aging and antioxidant properties. In this study, we develop four new rose varieties (named
Ever-rose
) that are fragrant, pest resistant, and easy to grow. Subsequently, we evaluate the properties of
Ever-rose
and its potential for use in anti-aging products.
Methods
The chemical composition of
Ever-rose
was determined using ultra-high-performance liquid chromatography triple time-of-flight mass spectrometry/mass spectrometry. The antioxidant activity of the
Ever-rose
extract was evaluated using various assays, including superoxide dismutase activity, 2,2-diphenyl-1-picrylhydrazyl radical-scavenging capacity, and xanthine oxidase activity. The variations in proteolytic matrix metalloproteinase-1 expression, collagen content after ultraviolet (UV) irradiation, and reactive-oxygen-species (ROS) levels after infrared A (IRA) treatment were evaluated. The variations in cell elasticity were assessed via atomic force microscopy.
Results
The petal extracts of
Ever-rose
(named ER004(P), ER011(P), ER012(P), and ER015(P)) showed good antioxidant activity. They effectively inhibited UV irradiation-induced MMP-1 expression and IRA irradiation-induced increase in mitochondrial ROS levels. Additionally, they inhibited variations in cell shape and elasticity as aging progressed. In particular, ER011(P) demonstrated the best anti-aging and antioxidant effects.
Conclusion
The newly developed
Ever-rose
showed excellent antioxidant and anti-aging effects. In particular, ER011(P) demonstrated the best properties owing to its high antioxidant content. Hence, it exhibits significant potential as a functional cosmetic ingredient.
Graphical Abstract