Syndrome of Irreversible Lithium-Effectuated NeuroToxicity

Lithium has a narrow therapeutic window. Frequent monitoring of both serum levels and clinical signs of toxicity is warranted because toxicity may be present even when concentrations are within the therapeutic range. We report the case of a man with lithium poisoning, with persistent neurologic sign...

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Bibliographic Details
Published in:	Acta medica portuguesa Vol. 30; no. 2; pp. 151 - 153
Main Authors:	Silva, Ana Luísa, Ourique, Carolina, Martins, Filipe, Friões, Fernando
Format:	Journal Article
Language:	Portuguese
Published:	Portugal Ordem dos Médicos 27-02-2017
Subjects:	Aged Humans Lithium Compounds - poisoning Lítio/efeitos adversos Male Neurotoxicity Syndromes - etiology Síndromes de Neurotoxicidade/etiologia
Online Access:	Get full text
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Summary:	Lithium has a narrow therapeutic window. Frequent monitoring of both serum levels and clinical signs of toxicity is warranted because toxicity may be present even when concentrations are within the therapeutic range. We report the case of a man with lithium poisoning, with persistent neurologic signs and symptoms even after removal of lithium from circulation - a diagnosis of syndrome of irreversible lithium-effectuated neurotoxicity (SILENT) was made.
ISSN:	0870-399X 1646-0758
DOI:	10.20344/amp.7907