Treatment of Libman-Sacks endocarditis by combination of warfarin and immunosuppressive therapy

Antiphospholipid syndrome (APS) is a clinical disorder that creates an increased risk of arterial or venous thrombotic events or pregnancy-associated complications and includes the presence of autoantibodies against negatively charged phospholipids. This syndrome is often associated with systemic au...

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Bibliographic Details
Published in:Türk Kardiyoloji Derneği arşivi Vol. 47; no. 8; pp. 687 - 690
Main Authors: Mehmet Rasih Sonsöz, Rukiye Dilara Tekin, Ahmet Gül, Zehra Buğra, Dursun Atılgan
Format: Journal Article
Language:English
Published: KARE Publishing 01-12-2019
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Summary:Antiphospholipid syndrome (APS) is a clinical disorder that creates an increased risk of arterial or venous thrombotic events or pregnancy-associated complications and includes the presence of autoantibodies against negatively charged phospholipids. This syndrome is often associated with systemic autoimmune diseases, such as systemic lupus erythematosus (SLE). Libman-Sacks endocarditis is a form of non-bacterial thrombotic endocarditis and is infrequently seen in APS. There are few data documenting the echocardiographic response of APS valve disease to medical treatment. This is an unusual case of a young female patient with SLE and APS who had chorea and non-bacterial thrombotic aortic valve endocarditis. Echocardiography revealed that the vegetation had receded after a combination of warfarin and immunosuppressive therapy.
ISSN:1016-5169
DOI:10.5543/tkda.2019.29213