Hepatitis C Virus Antibodies and Vitiligo Disease

Vitiligo is a common skin disorder, characterized by depigmented patches due to selective destruction of melanocytes. The etiology of this disease is unknown. A number of hypotheses including viral theory have been proposed to explain the etiology. To determine the prevalence of antibody to hepatiti...

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Bibliographic Details
Published in:	Iranian journal of public health Vol. 34; no. 1; pp. 23 - 26
Main Authors:	Z Jadali, MB Eslami, MH Sanati, P Mansouri, M Mahmoudi, N Maghsoudi, F Esfahanian
Format:	Journal Article
Language:	English
Published:	Tehran University of Medical Sciences 01-06-2005
Subjects:	Hepatitis C virus Vitiligo
Online Access:	Get full text
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Summary:	Vitiligo is a common skin disorder, characterized by depigmented patches due to selective destruction of melanocytes. The etiology of this disease is unknown. A number of hypotheses including viral theory have been proposed to explain the etiology. To determine the prevalence of antibody to hepatitis C virus infection in vitiligo patients, the present study was performed. Third generation ELISA test was used for detection of antibodies to HCV in human sera. All normal controls were anti-HCV negative whereas only one patient was positive for anti-HCV and there was no significant difference in the prevalence of anti-HCV between patients and controls. These results indicate that hepatitis C virus has not a direct causal role in the pathogenesis of vitiligo, however, this does not rul out a "hit and run" virus induced disease.
ISSN:	2251-6085