ALK-positive anaplastic large cell lymphoma of paranasal sinuses: two cases report and literature review

ALK-positive anaplastic large cell lymphoma is a rare T-cell lymphoma with ALK gene rearrangement that develops in children and young adults. The disease almost always affects the lymph nodes, and extranodal areas are also frequently involved. This article describes two cases of atypical localizatio...

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Bibliographic Details
Published in:	Arkhiv patologii Vol. 86; no. 4; p. 42
Main Authors:	Abramov, D S, Fedorova, A S, Tuzova, E A, Myakova, N V, Konovalov, D M
Format:	Journal Article
Language:	English Russian
Published:	Russia (Federation) 2024
Subjects:	Adult Anaplastic Lymphoma Kinase - genetics Female Gene Rearrangement Humans Lymphoma, Large-Cell, Anaplastic - diagnosis Lymphoma, Large-Cell, Anaplastic - genetics Lymphoma, Large-Cell, Anaplastic - pathology Male Paranasal Sinus Neoplasms - diagnosis Paranasal Sinus Neoplasms - genetics Paranasal Sinus Neoplasms - metabolism Paranasal Sinus Neoplasms - pathology children paranasal sinuses ALK-positive anaplastic large cell lymphoma
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Summary:	ALK-positive anaplastic large cell lymphoma is a rare T-cell lymphoma with ALK gene rearrangement that develops in children and young adults. The disease almost always affects the lymph nodes, and extranodal areas are also frequently involved. This article describes two cases of atypical localization of ALK-positive anaplastic large cell lymphoma with involvement of the paranasal sinuses.
ISSN:	0004-1955
DOI:	10.17116/patol20248604142