ROLE OF SUSPENDED PARTICULATE MATTER IN ANGIOGENESIS EMPLOYING CROWN GALL TUMOR ASSAY
Objective: Aim of the study was to screen the suspended particulate matter for their role in enhancing angiogenesis employing crown gall tumor assay.Methods: Particulate matter (PM10) samples were collected, on glass fiber filter paper at the rate of 1.12–1.14 m3/min for 8 hr using high volume sampl...
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| Published in: | International journal of pharmacy and pharmaceutical sciences Vol. 9; no. 1; p. 34 |
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| Main Authors: | , |
| Format: | Journal Article |
| Language: | English |
| Published: |
31-12-2016
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| Online Access: | Get full text |
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| Summary: | Objective: Aim of the study was to screen the suspended particulate matter for their role in enhancing angiogenesis employing crown gall tumor assay.Methods: Particulate matter (PM10) samples were collected, on glass fiber filter paper at the rate of 1.12–1.14 m3/min for 8 hr using high volume sampler, from six different sites of Amritsar city. Aqueous extracts of suspended particulate matter were prepared using a mechanical shaker for 24 hour and the filtrate was centrifuged and lyophilized.Results: Maximum (34.67±1.764) tumors were induced by samples collected from Crystal chowk whereas tumor inducing ratio (TIR) was found to be comparably high for two sites viz., Crystal chowk and Bhandari bridge.Conclusion: High tumor inducing ratio at the above-mentioned sites was correlated to high traffic emission from automobile exhaust. Crown gall tumor assay has been proved to be rapid, economical and reliable screening assay for angiogenesis agent. |
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| ISSN: | 0975-1491 0975-1491 |
| DOI: | 10.22159/ijpps.2017v9i1.15440 |