Inhibitors of lysosomal cysteine proteases

Inhibitors of lysosomal cysteine proteases

The review is devoted to the inhibitors of cysteine proteinases which are believed to be very important in many biochemical processes of living organisms. They participate in the development and progression of numerous diseases that involve abnormal protein turnover. One of the main regulators of th...

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Bibliographic Details
Published in:Biopolimery i kletka Vol. 27; no. 3; pp. 181 - 192
Main Authors: Chorna, V. I., Lyanna, O. L.
Format: Journal Article
Language:English
Published: Kiev Natsional'na Akademiya Nauk Ukrainy - National Academy of Sciences of Ukraine 20-05-2011
Subjects:
Cysteine
Protein turnover
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Summary:The review is devoted to the inhibitors of cysteine proteinases which are believed to be very important in many biochemical processes of living organisms. They participate in the development and progression of numerous diseases that involve abnormal protein turnover. One of the main regulators of these proteinases is their specific inhibitors: cystatins. The aim of this review was to present current knowledge about endogenous inhibitors of lysosomal cysteine proteases and their synthetic analogs.
ISSN:0233-7657
1993-6842
DOI:10.7124/bc.0000B8