PREVENTIVE UTILITY OF THE INTEGRATION OF LIFEʼS SIMPLE 7 DESIGNED BY THE AMERICAN HEART ASSOCIATION AND THE MODEL FOR CARDIOVASCULAR RISK PREDICTION IBERSCORE

• Published in: Journal of hypertension Vol. 37 Suppl 1; p. e157
• Main Authors: Ruilope, L.M, Fernandez-Labandera, C, Quevedo-Aguado, L, Martinez-Munoz, P, Catalina-Romero, C, Valdivielso, P, Angel Sanchez-Chaparro, M, Calvo-Bonacho, E
• Format: Journal Article
• Language: English
• Published: Copyright Wolters Kluwer Health, Inc. All rights reserved 01-07-2019
• ISSN: 0263-6352; 1473-5598
• DOI: 10.1097/01.hjh.0000572008.97277.e5

OBJECTIVE:To assess the clinical usefulness of the application of the predictive model of cardiovascular risk (CVR) IberScore combined with the recommendations of Lifeʼs Simple 7 (LS7) of the American Heart Association (AHA) in a working population.
DESIGN AND METHOD:IberScore model is a predictive function for fatal and non-fatal cardiovascular (CV) events derived from a cohort of 774,404 workers (70.4% of the target population) between 16–65 years (average of 35.7 (SD = 10.7)) without CV disease at admission, which was followed for a period of 10 years. Age, sex, total cholesterol, HDL, SBP, glycemia, obesity and a history of dyslipidemia, hypertension and diabetes were used as factors of CVR. Using this model, patients were classified into 4 risk levels. It was also assessed the ideal health status according to the recommendations of Lifeʼs Simple 7 (which includes healthy diet, physical activity, smoking cessation, BMI < 25 kg/m2, total cholesterol without treatment <200 mg/dl, blood pressure without treatment <120/80 mmHg and basal glycemia <100 mg/dl). Finally, these classifications were compared with the appearance of CV events in a 10-year follow-up.
RESULTS:The results showed a high sensitivity (given that the predictive capacity reached 82% of the cardiovascular events) by using the IberScore, a logistic flexible parametric model to predict 10-year cardiovascular risk. Likewise, the clinical usefulness of the Lifeʼs Simple 7 recommendations could be verified in order to reduce the incidence of total CV events (fatal and non-fatal).
CONCLUSIONS:The integration of the predictive model IberScore with the preventive recommendations Lifeʼs simple 7 of the AHA applied to the working population would allow a more efficient cardiovascular prevention.