SCHWANNOMA IN THE LOWER LIP: A CASE REPORT

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology Vol. 136; no. 1; p. e78
• Main Authors: ROCHA, Gabriela Fonseca, Gonçalves, Moisés Willian Aparecido, de Almeida e Silva, Larissa Doalla, de Miranda, João Luiz, Silva, Evanio Vilela, León, Jorge Esquiche, Mesquita, Ana Terezinha Marques
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01-07-2023
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2023.03.285

Schwannoma is a benign tumor derived from Schwann cells. About 25% of all schwannomas are diagnosed in the head and neck region, but only 1% in the oral cavity. The intraoral lesions show a predilection for the tongue, followed by palate, buccal mucosa, and lip. A 26-year-old male was referred, complaining of a "cyst on the lower lip" which began 5 years ago. Intraoral examination showed a painless nodule, normal color, smooth surface, and fibroelastic consistency, located on the lower lip. An excisional biopsy was performed, and histopathological examination showed a well-circumscribed, encapsulated tumor with a predominantly typical Antoni A pattern, present throughout the tumor. Immunohistochemical analysis showed positive results for S100, CD56, and CD34. The diagnosis of Schwannoma was established. The patient is undergoing follow-up, with no signs of lesion recurrence after 1 year. Schwannoma should be considered in the differential diagnosis of nodular lesions on the lip.