RETROSPECTIVE AND OBSERVATIONAL STUDY OF POTENTIALLY MALIGNANT DISORDERS IN A PATHOLOGICAL ANATOMY SERVICE

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology Vol. 136; no. 1; p. e46
• Main Authors: FREITAS, Janaína Martins, GOMES, Bárbara Quaresma, Araújo, Samuel Sousa SIVIERI, NOMELINI, Márcia Helena Destro, HENRIQUE, Paulo Roberto, SERVATO, João Paulo Silva, de Araújo, Marcelo SIVIERI
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01-07-2023
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2023.03.134

To evaluate a study population of a pathological anatomy service that was affected by potentially malignant disorders (PMDs), through a retrospective and observational study.
Our study examined 144 cases of PMDs over a 20-year period, analyzing the frequency of such characteristics as age, gender, ethnicity, lesion location, histopathological diagnosis, associated risk factors, and presence of epithelial dysplasia. A follow-up clinical examination was also performed.
Higher prevalence was observed in white females, in an age group of 61-70 years, and the buccal mucosa was the most affected site. Leukoplakia was the most frequent PMD; associated risk factors, alcohol, and tobacco in male patients were the most prevalent; and six cases of epithelial dysplasia were identified. Thirty-one patients attended the follow-up dental appointment, and 12 exhibited recurrences of oral lesions.
There is a lack of epidemiological surveys and follow-up clinical examinations for PMDs in Brazil and worldwide for the early detection of lesions. The difficulty in keeping the registration data of public healthcare services up-to-date, as well as low motivation and patient support for prolonged clinical follow-up, were also observed.