CLINICAL AND EPIDEMIOLOGIC PROFILE OF ORAL EPIDERMOID CARCINOMA IN YOUNG ADULTS PATIENTS: SYSTEMATIC REVIEW

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology Vol. 130; no. 3; pp. e274 - e275
• Main Authors: LEMOS, LUISA MADEIRA, SILVA, GABRIEL GOMES DA, PINHEIRO, JULIANA CAMPOS, MORAIS, EVERTON FREITAS DE, BARROS, CAIO CéSAR DA SILVA, LEITE, RAFAELLA BASTOS
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01-09-2020
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2020.04.750

Objective: To identify and describe clinical and epidemiologic profile of oral squamous cell carcinoma (OSCC) in young adults. Study Design: A systematic literature review was carried out in electronic databases Lilacs, SciELO, PubMed, and Periódico Capes, whose descriptors were: oral cancer, oral squamous cell carcinoma, epidemiology and young patient, in English, Spanish, and Portuguese, between January 2003 and January 2016. The review identified 348 articles, 8 of them had as main objective to evaluate clinical and epidemiologic aspects of OSCC in young adults between 20 and 45 years. Results: Tobacco use and/or alcoholism stand out among the etiologic factors related to OSCC. The tongue was the most affected region in oral cavity, followed by the lower lip and buccal floor. Regarding clinical tumor stage, it was observed, in 4 studies, that type III and IV prevailed, and regional-type metastasis was the most common. The predominant treatment associated surgery with radiotherapy, followed by isolated surgery. Conclusion: Further studies are required to define the clinical and epidemiologic characteristics of the tumor in this population and also to standardize the age group referring to the term "young adult." This information may enable the development of a primary prevention program for patients with OSCC.