Evaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with 14 C-labeled ( R )-6-[Amino(4- chlorophenyl)(1-methyl-1 H -imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1 H )-quinolinone (R115777), a Farnesyl Transferase Inhibitor

Evaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with 14 C-labeled ( R )-6-[Amino(4- chlorophenyl)(1-methyl-1 H -imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1 H )-quinolinone (R115777), a Farnesyl Transferase Inhibitor

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Bibliographic Details
Published in:Drug metabolism and disposition Vol. 30; no. 7; pp. 823 - 830
Main Authors: Garner, R. C., Goris, I., Laenen, A. A. E., Vanhoutte, E., Meuldermans, W., Gregory, S., Garner, J. V., Leong, D., Whattam, M., Calam, A., Snel, C. A. W.
Format: Journal Article
Language:English
Published: 01-07-2002
Online Access:Get full text
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Description
ISSN:0090-9556
1521-009X
DOI:10.1124/dmd.30.7.823