Cover Picture: Synthesis and Evaluation of Indatraline-Based Inhibitors for Trypanothione Reductase / Design, Synthesis and Biological Evaluation of Novel Inhibitors of Trypanosoma brucei Pteridine Reductase 1 / Modified 5′-Trityl Nucleosides as Inhibitors of Plasmodium falciparum dUTPase (ChemMedChem 2/2011)

• Published in: ChemMedChem Vol. 6; no. 2; p. 209
• Main Authors: Walton, Jeffrey G. A., Jones, Deuan C., Kiuru, Paula, Durie, Alastair J., Westwood, Nicholas J., Fairlamb, Alan H., Spinks, Daniel, Ong, Han B., Mpamhanga, Chidochangu P., Shanks, Emma J., Robinson, David A., Collie, Iain T., Read, Kevin D., Frearson, Julie A., Wyatt, Paul G., Brenk, Ruth, Gilbert, Ian H., Ruda, Gian Filippo, Nguyen, Corinne, Ziemkowski, Przemysław, Felczak, Krzysztof, Kasinathan, Ganasan, Musso-Buendia, Alexander, Sund, Christian, Zhou, Xiao Xiong, Kaiser, Marcel, Ruiz-Pérez, Luis M., Brun, Reto, Kulikowski, Tadeusz, Johansson, Nils Gunnar, González-Pacanowska, Dolores
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 07-02-2011
• Subjects: antiprotozoal agents; drug discovery; dUTPase; indatraline; malaria; Nazarov reaction; nucleoside chemistry; nucleotide metabolism; Plasmodium falciparum; pteridine reductase; structure-based drug design; Trypanosoma brucei; trypanothione reductase
• ISSN: 1860-7179; 1860-7187
• DOI: 10.1002/cmdc.201190000