Evaluating the safety of influenza vaccine using a claims-based health system

• Published in: Vaccine Vol. 31; no. 50; pp. 5975 - 5982
• Main Authors: McCarthy, Natalie L, Gee, Julianne, Lin, Nancy D, Thyagarajan, Veena, Pan, Yi, Su, Sue, Turnbull, Bruce, Chan, K. Arnold, Weintraub, Eric
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 05-12-2013; Elsevier; Elsevier Limited
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Allergy and Immunology; Anaphylaxis; Applied microbiology; Bells palsy; Biological and medical sciences; Centers for Disease Control and Prevention; Child; Child, Preschool; Claims; Cohort Studies; Confidence intervals; Drug-Related Side Effects and Adverse Reactions - epidemiology; Drug-Related Side Effects and Adverse Reactions - pathology; Female; Fundamental and applied biological sciences. Psychology; Guillain-Barre Syndrome; Guillain-Barre Syndrome - epidemiology; Guillain-Barre Syndrome - pathology; H1N1; Health insurance; Health Insurance Portability & Accountability Act 1996-US; Humans; Immunization; Incidence; Infant; Infant, Newborn; Influenza; Influenza Vaccines - administration & dosage; Influenza Vaccines - adverse effects; Influenza, Human - prevention & control; Insurance Claim Review; Male; Medical records; Microbiology; Middle Aged; monitoring; Nervous system; pandemic; patients; Pharmacy; Retrospective Studies; risk; Seasons; seizures; Seizures - epidemiology; Seizures - pathology; vaccination; Vaccine safety; Vaccines; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects); Young Adult; United States > US; Vaccine safety; Claims; H1N1; Influenza; Infection; Viral disease; Influenza A; Vaccine; Influenzavirus A(H1N1)
• ISSN: 0264-410X; 1873-2518
• DOI: 10.1016/j.vaccine.2013.10.031

Highlights • Influenza vaccine safety with claims-based data in 2009–2010 and 2010–2011 seasons. • No increased risk found after H1N1 in 2009–2010 season. • No increased risk found after TIV in 2010–2011 season. • After claims review, no increased risk for pre-specified outcomes in either season.