Emotional disorders in pairs of patients and their family members during and after ICU stay

• Published in: PloS one Vol. 10; no. 1; p. e0115332
• Main Authors: Fumis, Renata Rego Lins, Ranzani, Otavio T, Martins, Paulo Sérgio, Schettino, Guilherme
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 23-01-2015; Public Library of Science (PLoS)
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Anxiety; Anxiety - epidemiology; Behavior disorders; Cancer; Critical Care - psychology; Depression (Mood disorder); Depression - epidemiology; Discharge; Emotions; Families & family life; Family - psychology; Female; Hospitals; Humans; Intensive care; Intensive Care Units; Length of Stay; Male; Mental depression; Mental disorders; Middle Aged; Patients; Patients - psychology; Post traumatic stress disorder; Posttraumatic stress disorder; Spirituality; Stress Disorders, Post-Traumatic - epidemiology; Ventilators
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0115332

Patients and family members undergo different experiences of suffering from emotional disorders during ICU stay and after ICU discharge. The purpose of this study was to compare the incidence of anxiety, depression and post-traumatic stress disorder (PTSD) symptoms in pairs (patient and respective family member), during stay at an open visit ICU and at 30 and 90-days post-ICU discharge. We hypothesized that there was a positive correlation with the severity of symptoms among pairs and different patterns of suffering over time.
A prospective study was conducted in a 22-bed adult general ICU including patients with >48 hours stay. The Hospital Anxiety and Depression Scale (HADS) was completed by the pairs (patients/respective family member). Interviews were made by phone at 30 and 90-days post-ICU discharge using the Impact of Event Scale (IES) and the HADS. Multivariate models were constructed to predict IES score at 30 days for patients and family members.
Four hundred and seventy one family members and 289 patients were interviewed in the ICU forming 184 pairs for analysis. Regarding HADS score, patients presented less symptoms than family members of patients who survived and who deceased at 30 and 90-days (p<0.001). However, family members of patients who deceased scored higher anxiety and depression symptoms (p = 0.048) at 90-days when compared with family members of patients who survived. Patients and family members at 30-days had a similar IES score, but it was higher in family members at 90-days (p = 0.019). For both family members and patients, age and symptoms of anxiety and depression during ICU were the major determinants for PTSD at 30-days.
Anxiety, depression and PTSD symptoms were higher in family members than in the patients. Furthermore, these symptoms in family members persisted at 3 months, while they decreased in patients.