Temporomandibular joint disorder complaints in tinnitus: further hints for a putative tinnitus subtype

• Published in: PloS one Vol. 7; no. 6; p. e38887
• Main Authors: Vielsmeier, Veronika, Strutz, Jürgen, Kleinjung, Tobias, Schecklmann, Martin, Kreuzer, Peter Michael, Landgrebe, Michael, Langguth, Berthold
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 19-06-2012; Public Library of Science (PLoS)
• Subjects: Acoustics; Adult; Aged; Analysis; Brain research; Clinical outcomes; Comorbidity; Data analysis; Data processing; Demographics; Development and progression; Etiology; Female; Health aspects; Hearing loss; Humans; Loudness; Male; Maneuvers; Medical research; Medicine; Mental depression; Middle Aged; Otolaryngology; Patient assessment; Patients; Psychiatry; Psychotherapy; Quality of life; Questionnaires; Ratings; Replicating; Risk analysis; Risk factors; Sound; Statistical analysis; Statistical analysis of data; Surveys and Questionnaires; Temporomandibular joint; Temporomandibular Joint Disorders - complications; Tinnitus; Tinnitus - epidemiology; Tinnitus - etiology; Whiplash; Aachen Germany
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0038887

Tinnitus is considered to be highly heterogeneous with respect to its etiology, its comorbidities and the response to specific interventions. Subtyping is recommended, but it remains to be determined which criteria are useful, since it has not yet been clearly demonstrated whether and to which extent etiologic factors, comorbid states and interventional response are related to each other and are thus applicable for subtyping tinnitus. Analyzing the Tinnitus Research Initiative Database we differentiated patients according to presence or absence of comorbid temporomandibular joint (TMJ) disorder complaints and compared the two groups with respect to etiologic factors.
1204 Tinnitus patients from the Tinnitus Research Initiative (TRI) Database with and without subjective TMJ complaints were compared with respect to demographic, tinnitus and audiological characteristics, questionnaires, and numeric ratings. Data were analysed according to a predefined statistical analysis plan.
Tinnitus patients with TMJ complaints (22% of the whole group) were significantly younger, had a lower age at tinnitus onset, and were more frequently female. They could modulate or mask their tinnitus more frequently by somatic maneuvers and by music or sound stimulation. Groups did not significantly differ for tinnitus duration, type of onset (gradual/abrupt), onset related events (whiplash etc.), character (pulsatile or not), hyperacusis, hearing impairment, tinnitus distress, depression, quality of life and subjective ratings (loudness etc.).
Replicating previous work in tinnitus patients with TMJ complaints, classical risk factors for tinnitus like older age and male gender are less relevant in tinnitus patients with TMJ complaints. By demonstrating group differences for modulation of tinnitus by movements and sounds our data further support the notion that tinnitus with TMJ complaints represents a subgroup of tinnitus with clinical features that are highly relevant for specific therapeutic management.