Quality of life after radical cystectomy for bladder cancer in men with an ileal conduit or continent urinary diversion: A comparative study

• Published in: Urology annals Vol. 5; no. 3; pp. 190 - 196
• Main Authors: Asgari, M, Safarinejad, M, Shakhssalim, N, Soleimani, M, Shahabi, A, Amini, E
• Format: Journal Article
• Language: English
• Published: India Medknow Publications 01-07-2013; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd; Wolters Kluwer Medknow Publications
• Subjects: Bladder cancer; Care and treatment; Clinical outcomes; continent diversion; Cystectomy; Health aspects; Intubation; Mens health; Methods; Original; orthotopic bladder substitution; Ostomy; Patient education; Patient outcomes; Patient satisfaction; Quality of life; Questionnaires; radical cystectomy; Self image; Studies; Urinary diversion; continent diversion; radical cystectomy; quality of life; Bladder cancer; orthotopic bladder substitution
• ISSN: 0974-7796; 0974-7834
• DOI: 10.4103/0974-7796.115747

Aim: To investigate quality of life (QoL) domains with three forms of urinary diversions, including ileal conduit, MAINZ pouch, and orthotopic ileal neobladder after radical cystectomy in men with muscle-invasive bladder cancer.
Materials and Methods: In a prospective study, 149 men underwent radical cystectomy and urinary diversion (70 ileal conduit, 16 MAINZ pouch, and 63 orthotopic ileal neobladder). Different domains of QoL, including general and physical conditions, psychological status, social status, sexual life, diversion-related symptoms, and satisfaction with the treatment were assessed using an author constructed questionnaire. Assessment was performed at three months postoperatively.
Results: In questions addressing psychological status, social status, and sexual life, patients with continent diversion had a more favorable outcome ( P = 0.002, P = 0.01, and P = 0.002, respectively). The rate of erectile dysfunction did not differ significantly between the three groups ( P = 0.21). The rate and global satisfaction was higher with the MAINZ pouch (68.7%) and ileal neobladder (76.2%) as compared with the ileal conduit group (52.8%) ( P = 0.002).
Conclusion: Continent urinary diversion after radical cystectomy provides better results in terms of QoL as compared with ileal conduit diversion.