Aerocyanidin, a new antibiotic produced by Chromobacterium violaceum

Aerocyanidin, a new antibiotic containing an isonitrile group, has been isolated from fermentations of Chromobacterium violaceum ATCC 53434. Structure 1 was assigned on the bais of spectroscopic characterization of the antibiotic and of a degradation product that results from treatment with base. Th...

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Bibliographic Details
Published in:	Journal of antibiotics Vol. 41; no. 4; p. 454
Main Authors:	Parker, W L, Rathnum, M L, Johnson, J H, Wells, J S, Principe, P A, Sykes, R B
Format:	Journal Article
Language:	English
Published:	Japan 1988
Subjects:	Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Chemical Phenomena Chemistry Chromobacterium - metabolism Fermentation Molecular Conformation Nitriles - isolation & purification Nitriles - pharmacology
Online Access:	Get more information
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Summary:	Aerocyanidin, a new antibiotic containing an isonitrile group, has been isolated from fermentations of Chromobacterium violaceum ATCC 53434. Structure 1 was assigned on the bais of spectroscopic characterization of the antibiotic and of a degradation product that results from treatment with base. The antibiotic is primarily active against Gram-positive bacteria.
ISSN:	0021-8820
DOI:	10.7164/antibiotics.41.454