Memnobotrins and memnoconols: novel metabolites from Memnoniella echinata

Four novel metabolites have been isolated from a rice culture of Memnoniella echinata (JS6308) by solvent extraction and radial silica chromatography. The structures were elucidated by spectroscopic techniques, and the absolute stereochemistry of memnobotrin A determined by X-ray crystallography.

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Bibliographic Details
Published in:	Journal of antibiotics Vol. 52; no. 11; p. 988
Main Authors:	Hinkley, S F, Fettinger, J C, Dudley, K, Jarvis, B B
Format:	Journal Article
Language:	English
Published:	Japan 1999
Subjects:	Antibiotics, Antineoplastic - chemistry Antibiotics, Antineoplastic - isolation & purification Antibiotics, Antineoplastic - pharmacology Benzofurans - chemistry Benzofurans - isolation & purification Benzofurans - pharmacology Crystallography, X-Ray Fatty Alcohols - chemistry Fatty Alcohols - isolation & purification Fatty Alcohols - pharmacology Fermentation Heterocyclic Compounds, 4 or More Rings - chemistry Heterocyclic Compounds, 4 or More Rings - isolation & purification Heterocyclic Compounds, 4 or More Rings - pharmacology Humans Mitosporic Fungi - metabolism Molecular Conformation Tumor Cells, Cultured
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Description
Summary:	Four novel metabolites have been isolated from a rice culture of Memnoniella echinata (JS6308) by solvent extraction and radial silica chromatography. The structures were elucidated by spectroscopic techniques, and the absolute stereochemistry of memnobotrin A determined by X-ray crystallography.
ISSN:	0021-8820
DOI:	10.7164/antibiotics.52.988