Rapid Detection of Mutation in RRDR of rpo B Gene for Rifampicin Resistance in MDR-Pulmonary Tuberculosis by DNA Sequencing

To detect the site of mutation in RRDR of rpo B gene for rifampicin resistance in MDR-TB by DNA sequencing. 50 MDR-TB patients were enrolled in our study after informed written consent. Mycobacterial DNA was extracted from sputum samples by Universal Sample Processing (USP) method and RRDR of rpo B...

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Bibliographic Details
Published in:	Indian journal of clinical biochemistry Vol. 25; no. 3; pp. 315 - 318
Main Authors:	Patra, Surajeet Kumar, Jain, Anju, Sherwal, B. L., Khanna, Ashwani
Format:	Journal Article
Language:	English
Published:	India Springer-Verlag 01-07-2010 Springer Springer Nature B.V
Subjects:	Antibiotics Biochemistry Biomedical and Life Sciences Chemistry/Food Science Codon Deoxyribonucleic acid DNA DNA sequencing Drug resistance Genes Genetic aspects Genetic research Life Sciences Medical research Medicine, Experimental Microbiology Mutation Mycobacterium Nucleotide sequencing Original ; Laboratory Documentation Original Article; Laboratory Documentation Pathology Pulmonary tuberculosis Rifampin Tuberculosis Tuberculosis rpo B gene Rifampicin resistance Multidrug resistance
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