Regulation of proteinaceous effector expression in phytopathogenic fungi

• Published in: PLoS pathogens Vol. 13; no. 4; p. e1006241
• Main Authors: Tan, Kar-Chun, Oliver, Richard P
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01-04-2017; Public Library of Science (PLoS)
• Subjects: Amino acids; Analysis; Animals; Biology and Life Sciences; Chromosomes; Crop diseases; Disease susceptibility; Effectors; Endosomes; Fungal Proteins - genetics; Fungal Proteins - metabolism; Fungi; Fungi - pathogenicity; Gene expression; Genetic aspects; Genomes; Genomics; Health aspects; Host-Pathogen Interactions - physiology; Humans; Immune system; Infections; Medicine and Health Sciences; Microorganisms; Mutation; Necrosis; Pathogenesis; Pathogens; Physiological aspects; Phytopathogenic fungi; Plant Diseases - microbiology; Plants - microbiology; Proteins; R&D; Research & development; Review; Studies; Transcription factors; Transcription Factors - metabolism; Virulence; Western Australia Australia
• ISSN: 1553-7374; 1553-7366; 1553-7374
• DOI: 10.1371/journal.ppat.1006241

Effectors are molecules used by microbial pathogens to facilitate infection via effector-triggered susceptibility or tissue necrosis in their host. Much research has been focussed on the identification and elucidating the function of fungal effectors during plant pathogenesis. By comparison, knowledge of how phytopathogenic fungi regulate the expression of effector genes has been lagging. Several recent studies have illustrated the role of various transcription factors, chromosome-based control, effector epistasis, and mobilisation of endosomes within the fungal hyphae in regulating effector expression and virulence on the host plant. Improved knowledge of effector regulation is likely to assist in improving novel crop protection strategies.