Cutavirus in Cutaneous Malignant Melanoma

• Published in: Emerging infectious diseases Vol. 23; no. 2; pp. 363 - 365
• Main Authors: Mollerup, Sarah, Fridholm, Helena, Vinner, Lasse, Kjartansdóttir, Kristín Rós, Friis-Nielsen, Jens, Asplund, Maria, Herrera, Jose A R, Steiniche, Torben, Mourier, Tobias, Brunak, Søren, Willerslev, Eske, Izarzugaza, Jose M G, Hansen, Anders J, Nielsen, Lars P
• Format: Journal Article
• Language: English
• Published: United States U.S. National Center for Infectious Diseases 01-02-2017; Centers for Disease Control and Prevention
• Subjects: bufavirus; Cancer; Complications and side effects; Cutavirus; Cutavirus in Cutaneous Malignant Melanoma, 2016; Development and progression; DNA, Viral; Genes, Viral; Humans; Letter; Letters to the Editor; malignant melanoma; Melanoma; Melanoma - diagnosis; Melanoma - etiology; Melanoma, Cutaneous Malignant; Oncology, Experimental; Parvoviridae Infections - complications; Parvoviridae Infections - diagnosis; Parvoviridae Infections - virology; Parvovirus; Parvovirus infections; Phylogeny; protoparvovirus; Risk factors; Sequence Analysis, DNA; Skin Neoplasms - diagnosis; Skin Neoplasms - etiology; viruses; bufavirus; protoparvovirus; viruses; malignant melanoma; Cutavirus; metagenomics; cancer; human; sequencing
• ISSN: 1080-6040; 1080-6059
• DOI: 10.3201/eid2302.161564

A novel human protoparvovirus related to human bufavirus and preliminarily named cutavirus has been discovered. We detected cutavirus in a sample of cutaneous malignant melanoma by using viral enrichment and high-throughput sequencing. The role of cutaviruses in cutaneous cancers remains to be investigated.