Effects of Lactobacillus acidophilus 43121 and a mixture of lactobacillus casei and bifidobacterium longum on the serum cholesterol level and fecal sterol excretion in hypercholesterolemia-induced pigs

• Published in: Bioscience, biotechnology, and biochemistry Vol. 72; no. 2; pp. 595 - 600
• Main Authors: Park, Y.H.(Korea Univ., Seoul (Korea R.)), Kim, J.G, Shin, Y.W, Kim, H.S, Kim, Y.J, Chun, T, Kim, S.H, Whang, K.Y
• Format: Journal Article
• Language: English
• Published: Tokyo Japan Society for Bioscience, Biotechnology, and Agrochemistry 01-02-2008; Japan Society for Bioscience Biotechnology and Agrochemistry; Oxford University Press
• Subjects: ALIMENT FERMENTE; ALIMENTOS FERMENTADOS; Animals; BACTERIAS ACIDOLACTICAS; BACTERIE LACTIQUE; Bifidobacterium - physiology; Bifidobacterium longum; Biological and medical sciences; CERDO; CHOLESTEROL; Cholesterol - blood; COLESTEROL; fecal sterol; Feces; FERMENTED FOODS; Fundamental and applied biological sciences. Psychology; HIPERLIPIDEMIA; Hypercholesterolemia - blood; Hypercholesterolemia - metabolism; Hypercholesterolemia - microbiology; HYPERLIPIDAEMIA; HYPERLIPIDEMIE; hypocholesterolemic effect; LACTIC ACID BACTERIA; LACTOBACILLUS ACIDOPHILUS; Lactobacillus acidophilus - physiology; LACTOBACILLUS CASEI; Lactobacillus casei - physiology; LIPOPROTEINAS; LIPOPROTEINE; LIPOPROTEINS; pig; PORCIN; Sterols - metabolism; SWINE; Lactic acid bacteria; Excretion; Actinomycetaceae; hypocholesterolemic effect; Bifidobacterium longum; Lactobacillus acidophilus; Cholesterol; Pig; Actinomycetales; fecal sterol; Vertebrata; Mammalia; Hypercholesterolemia; Bacteria; Lactobacillaceae; Serum; Actinomycetes; Artiodactyla; Feces; Ungulata; Sterol
• ISSN: 0916-8451; 1347-6947
• DOI: 10.1271/bbb.70581

The hypocholesterolemic effects of Lactobacillus acidophilus 43121 (43121) and a mixture of Lactobacillus casei and Bifidobacterium longum (MIX) were studied in hypercholesterolemia-induced pigs. Serum total cholesterol was decreased by supplementation of either 43121 or MIX, although, high-density lipoprotein cholesterol was not changed. The -hypocholesterolemic effect of 43121 and MIX was mainly due to bile acid dehydroxylation, this effect being supplementation-time dependent.