Plant pleiotropic drug resistance transporters： Transport mechanism, gene expression, and function

• Published in: Journal of integrative plant biology Vol. 56; no. 8; pp. 729 - 740
• Main Authors: Nuruzzaman, Mohammed, Zhang, Ru, Cao, Hong‐Zhe, Luo, Zhi‐Yong
• Format: Journal Article
• Language: English
• Published: China (Republic : 1949- ) Chinese Academy of Sciences 01-08-2014; Blackwell Publishing Ltd; Molecular Biology Research Center, School of Life Sciences, Central South University, Changsha 410078, China
• Subjects: ABC transporters; abiotic stress; ATP-Binding Cassette Transporters - metabolism; drug resistance; expression pattern; fungi; gene expression; Gene Expression Profiling; plant defense; plant hormones; Plant Proteins - metabolism; Plants - metabolism; pleiotropic drug resistance; secondary metabolites; transport mechanism; transporters; 传输机制; 基因表达; 植物激素; 次生代谢产物; 药物抗性; 转运体; 转运蛋白; 非生物胁迫; expression pattern; ABC transporters; pleiotropic drug resistance; plant defense; transport mechanism
• ISSN: 1672-9072; 1744-7909
• DOI: 10.1111/jipb.12196

Pleiotropic drug resistance (PDR) transporters belonging to the ABCG subfamily of ATP‐binding cassette (ABC) transporters are identified only in fungi and plants. Members of this family are expressed in plants in response to various biotic and abiotic stresses and transport a diverse array of molecules across membranes. Although their detailed transport mechanism is largely unknown, they play important roles in detoxification processes, preventing water loss, transport of phytohormones, and secondary metabolites. This review provides insights into transport mechanisms of plant PDR transporters, their expression profiles, and multitude functions in plants.