Feline Histoplasmosis in Brazil: Clinical and Laboratory Aspects and a Comparative Approach of Published Reports

• Published in: Mycopathologia (1975) Vol. 173; no. 2-3; pp. 193 - 197
• Main Authors: Brilhante, Raimunda Sâmia Nogueira, Coelho, Camila Gomes Virginio, Sidrim, José Júlio Costa, de Lima, Rita Amanda Chaves, Ribeiro, Joyce Fonteles, Cordeiro, Rossana Aguiar de, Castelo-Branco, Débora de Souza Collares Maia, Gomes, José Maurício Fonteles, Simões-Mattos, Lucilene, Mattos, Marcos Renato Franzosi, Beserra, Hugo Enrique Orsini, Nogueira, George Cândido, de Queiroz Pinheiro, Adriana, Rocha, Marcos Fábio Gadelha
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01-03-2012; Springer; Springer Nature B.V
• Subjects: Animals; Antibodies; Antifungal agents; Antifungal Agents - therapeutic use; Biomedical and Life Sciences; Biopsy; Blood tests; Brazil - epidemiology; Cat Diseases - diagnosis; Cat Diseases - drug therapy; Cat Diseases - epidemiology; Cat Diseases - microbiology; Cats; Drugs; Eukaryotic Microbiology; Female; Histoplasma - isolation & purification; Histoplasmosis; Histoplasmosis - diagnosis; Histoplasmosis - drug therapy; Histoplasmosis - epidemiology; Histoplasmosis - microbiology; Ketamine; Life Sciences; Male; Medical Microbiology; Microbial Ecology; Microbiology; Plant Sciences; Serological surveys; Serology; Skin; Skin diseases; Ulcers; Brazil; Cats; Serologic survey; Antifungal susceptibility profile; Felids
• ISSN: 0301-486X; 1573-0832
• DOI: 10.1007/s11046-011-9477-8

The present study described clinical and epidemiological aspects of three cases of feline histoplasmosis and compared them to previously described cases. A detailed mycological identification and antifungal susceptibility profile of each isolate are presented. Secondarily, a serological survey for anti-
Histoplasma
antibodies was performed with domestic and wild cats. Diseased animals presented nodular to ulcerated skin lesions and respiratory disorders as main clinical signs.
H.
capsulatum
var.
capsulatum
was isolated and the strains showed to be susceptible to antifungal drugs. Considering that feline histoplasmosis is uncommonly observed in veterinary clinics, diagnosis, and clinical management in endemic areas should be improved.