Immunomodulation for maxillofacial reconstructive surgery

Immunomodulation is a technique for the modulation of immune responses against graft material to improve surgical success rates. The main target cell for the immunomodulation is a macrophage because it is the reaction site of the graft and controls the healing process. Macrophages can be classified...

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Bibliographic Details
Published in:	Maxillofacial plastic and reconstructive surgery Vol. 42; no. 1; pp. 5 - 9
Main Author:	Kim, Seong-Gon
Format:	Journal Article
Language:	English
Published:	Singapore Springer Singapore 05-03-2020 Springer Nature B.V SpringerOpen 대한악안면성형재건외과학회
Subjects:	4-Hexylresorcinol Angiogenesis Cytokines Dental implants Dentistry Diabetic retinopathy Hydrophilic surfaces Hydroxyapatite Immunomodulation Inflammation Kinases Macrophage Medicine Oral and Maxillofacial Surgery Plastic Surgery Review Skin & tissue grafts Surgical outcomes Systemic diseases Trace elements Wound healing 치의학 4-Hexylresorcinol Wound healing Immunomodulation Macrophage
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Summary:	Immunomodulation is a technique for the modulation of immune responses against graft material to improve surgical success rates. The main target cell for the immunomodulation is a macrophage because it is the reaction site of the graft and controls the healing process. Macrophages can be classified into M1 and M2 types. Most immunomodulation techniques focus on the rapid differentiation of M2-type macrophage. An M2 inducer, 4-hexylresorcinol, has been recently identified and is used for bone grafts and dental implant coatings.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 https://jkamprs.springeropen.com/articles/10.1186/s40902-020-00249-4
ISSN:	2288-8101 2288-8586 2288-8586
DOI:	10.1186/s40902-020-00249-4