Nonalcoholic Fatty Liver Disease

• Published in: Canadian journal of gastroenterology & hepatology Vol. 2018; pp. 2097435 - 2
• Main Authors: Filipović, Branka, Forbes, Alastair, Tepeš, Bojan, Dumitraşcu, Dan L.
• Format: Journal Article
• Language: English
• Published: Egypt Hindawi 01-01-2018; Hindawi Limited
• Subjects: Atherosclerosis; Carcinoma; Cognitive ability; Diabetes; Disease Management; Drinking (Alcoholic beverages); Enzymes; Fatty liver; Global Health; Hepatocellular carcinoma; Humans; Incidence; Inflammation; Insulin; Insulin resistance; Investigations; Liver - diagnostic imaging; Liver cancer; Liver cirrhosis; Liver diseases; Medical schools; Metabolic syndrome; Non-alcoholic Fatty Liver Disease - diagnosis; Non-alcoholic Fatty Liver Disease - epidemiology; Non-alcoholic Fatty Liver Disease - therapy; Obesity; Older people; Patients; Polycystic ovary syndrome; Sarcopenia; Sleep apnea; Type 2 diabetes; Weight control
• ISSN: 2291-2789; 2291-2797
• DOI: 10.1155/2018/2097435

NAFLD ranges over a wide spectrum, extending from nonalcoholic fatty liver (NAFL) which is generally benign, through to nonalcoholic steatohepatitis (NASH) to liver cirrhosis, end-stage liver disease, and even hepatocellular carcinoma (HCC) despite the absence of significant alcohol consumption.Z. Prokopowicz et al. are stressing the importance of the early diagnosis of NONAL in obese children and NAFLD predictive risk factors include increased waist circumference, elevated waist-hip ratio and waist-to-height ratio, and elevated total cholesterol, triglycerides, and fasting insulin as well as elevated glucose and insulin concentration in the OGTT and HOMA-IR index.Definitive conclusion is that the consumption of a low calorie diet enriched with olive oil, along with slight weight reduction, reinforces the desired effects of weight loss in improving the levels of the hepatic enzymes.