Proteobacteria : microbial signature of dysbiosis in gut microbiota

Highlights • Members of the phylum Proteobacteria have a low abundance in the gut of healthy humans. • We provide an overview of correlations between a bloom of Proteobacteria and a diseased state. • We explain driving mechanisms for the uncontrolled expansion of the Proteobacteria population. • Pro...

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Bibliographic Details
Published in:	Trends in biotechnology (Regular ed.) Vol. 33; no. 9; pp. 496 - 503
Main Authors:	Shin, Na-Ri, Whon, Tae Woong, Bae, Jin-Woo
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-09-2015 Elsevier Limited
Subjects:	Animals Balancing Biotechnology Communities Diabetes Diagnostic systems dysbiosis Dysbiosis - microbiology Environmental Microbiology Flora Gastrointestinal Microbiome Genotype & phenotype Health risks Homeostasis Human Humans Internal Medicine Malnutrition Mammals Metabolic disorders Microbial activity microbiota Microorganisms Nutrition research Obesity Proteobacteria Signatures Studies Taxonomy microbiota Proteobacteria dysbiosis
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Summary:	Highlights • Members of the phylum Proteobacteria have a low abundance in the gut of healthy humans. • We provide an overview of correlations between a bloom of Proteobacteria and a diseased state. • We explain driving mechanisms for the uncontrolled expansion of the Proteobacteria population. • Proteobacterial load is suggested as a potential diagnostic criterion for dysbiosis and disease.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 ObjectType-Article-1 ObjectType-Feature-2
ISSN:	0167-7799 1879-3096
DOI:	10.1016/j.tibtech.2015.06.011