Systematic genetic nomenclature for type VII secretion systems

• Published in: PLoS pathogens Vol. 5; no. 10; p. e1000507
• Main Authors: Bitter, Wilbert, Houben, Edith N G, Bottai, Daria, Brodin, Priscille, Brown, Eric J, Cox, Jeffery S, Derbyshire, Keith, Fortune, Sarah M, Gao, Lian-Yong, Liu, Jun, Gey van Pittius, Nicolaas C, Pym, Alexander S, Rubin, Eric J, Sherman, David R, Cole, Stewart T, Brosch, Roland
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01-10-2009; Public Library of Science (PLoS)
• Subjects: Antigens, Bacterial - genetics; Bacterial proteins; Bacterial Proteins - genetics; Comparative analysis; Gene loci; Genes, Bacterial; Genetic aspects; Genetics and Genomics/Functional Genomics; Genomes; Leprosy; Microbiology/Cellular Microbiology and Pathogenesis; Models, Genetic; Mycobacterium tuberculosis; Mycobacterium tuberculosis - genetics; Names; Opinion; Physiological aspects; Proteins; Secretion; Secretory Pathway - genetics; Sequence Homology, Amino Acid; Terminology as Topic; Tuberculosis; France
• ISSN: 1553-7374; 1553-7366; 1553-7374
• DOI: 10.1371/journal.ppat.1000507

 
[...]we would like to emphasize that the introduction of a uniform gene nomenclature for other secretion systems in Gram-negative bacteria (type II, type III) has facilitated comparative analysis of these systems. Amongst the different topology prediction programs that were used (TMHMM Server v. 2.0, MEMSAT3, Philius, SCAMPI, HMMTOP and Phobius) MEMSAT3 gave the correct prediction for the highest number of Ecc membrane proteins. [...]only the topology prediction results of TMHMM (used on the TubercuList server) and MEMSAT3 are shown.