Perioperative management of patient with Bombay blood group undergoing mitral valve replacement

• Published in: Indian journal of anaesthesia Vol. 59; no. 12; pp. 811 - 813
• Main Authors: Priye, Shio, Sathyanarayan, J, Shivaprakash, S, Reddy, Durgaprasad
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01-12-2015; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd; Wolters Kluwer Medknow Publications
• Subjects: ABO blood-group system; Antigens; Autologous blood donation; Blood & organ donations; Blood groups; Bombay blood group; cardiac surgery; Case Report; Coronary vessels; Genotype & phenotype; Health aspects; Heart valve replacement; Medical research; Methods; Ostomy; Patients; Perioperative care; Precision medicine; Surgery; Veins & arteries; India; Bombay blood group; cardiac surgery; Autologous blood donation
• ISSN: 0019-5049; 0976-2817
• DOI: 10.4103/0019-5049.171577

Bombay red blood cell phenotype is an extremely rare blood type for which patients can receive only autologous or Bombay phenotype red blood cells. We report a case of stenotic mitral valve with Bombay phenotype who underwent minimal invasive right lateral thoracotomy for the replacement of the mitral valve. A male patient from Bangladesh presented to the hospital with New York Heart Association III symptoms. His medical evaluation revealed severe mitral valve stenosis and mild aortic valve regurgitation. The patient received erythropoietin, intravenous iron succinate and folic acid tablets. Autologous blood transfusion was carried out. The mitral valve was replaced with a prosthetic valve successfully. After weaning off from cardiopulmonary bypass, heparinisation was corrected with protamine. Post-operatively, the patient received autologous red blood cells. The patient recovered after 1-day of inotropic support with adrenaline and milrinone, and diuretics and was discharged on the 5(th) post-operative day.