Host-seeking efficiency can explain population dynamics of the tsetse fly Glossina morsitans morsitans in response to host density decline

• Published in: PLoS neglected tropical diseases Vol. 11; no. 7; p. e0005730
• Main Authors: Lord, Jennifer S, Mthombothi, Zinhle, Lagat, Vitalis K, Atuhaire, Fatumah, Hargrove, John W
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 03-07-2017; Public Library of Science (PLoS)
• Subjects: African trypanosomiasis; Animals; Anthropogenic factors; Arthropods; Biology and Life Sciences; Blood; Density; Differential equations; Disease transmission; Dynamics; Efficiency; Feeding; Feeding Behavior; Feeds; Female; Females; Flies; Glossina morsitans morsitans; Host location; Hosts; Human influences; Immigration; Insect Vectors - growth & development; Insect Vectors - physiology; Insects; Male; Mathematical models; Medicine and Health Sciences; Models, Theoretical; Mortality; Offspring; Ordinary differential equations; People and Places; Physical Sciences; Population; Population density; Population Dynamics; Risk factors; Starvation; Temporal variations; Transmission; Tropical diseases; Trypanosoma; Trypanosoma brucei; Trypanosome; Trypanosomiasis, African - transmission; Tsetse Flies - growth & development; Tsetse Flies - physiology; Vector-borne diseases; Vectors; Zimbabwe; Zoonoses; Zimbabwe; South Africa
• ISSN: 1935-2735; 1935-2727; 1935-2735
• DOI: 10.1371/journal.pntd.0005730

Females of all blood-feeding arthropod vectors must find and feed on a host in order to produce offspring. For tsetse-vectors of the trypanosomes that cause human and animal African trypanosomiasis-the problem is more extreme, since both sexes feed solely on blood. Host location is thus essential both for survival and reproduction. Host population density should therefore be an important driver of population dynamics for haematophagous insects, and particularly for tsetse, but the role of host density is poorly understood. We investigate the issue using data on changes in numbers of tsetse (Glossina morsitans morsitans Westwood) caught during a host elimination experiment in Zimbabwe in the 1960s. During the experiment, numbers of flies caught declined by 95%. We aimed to assess whether models including starvation-dependent mortality could explain observed changes in tsetse numbers as host density declined. An ordinary differential equation model, including starvation-dependent mortality, captured the initial dynamics of the observed tsetse population. However, whereas small numbers of tsetse were caught throughout the host elimination exercise, the modelled population went extinct. Results of a spatially explicit agent-based model suggest that this discrepancy could be explained by immigration of tsetse into the experimental plot. Variation in host density, as a result of natural and anthropogenic factors, may influence tsetse population dynamics in space and time. This has implications for Trypanosoma brucei rhodesiense transmission. Increased tsetse mortality as a consequence of low host density may decrease trypanosome transmission, but hungrier flies may be more inclined to bite humans, thereby increasing the risk of transmission to humans. Our model provides a way of exploring the role of host density on tsetse population dynamics and could be incorporated into models of trypanosome transmission dynamics to better understand how spatio-temporal variation in host density impacts trypanosome prevalence in mammalian hosts.