Validity of a reported history of chickenpox in targeting varicella vaccination at susceptible adolescents in England

• Published in: Vaccine Vol. 32; no. 10; pp. 1213 - 1217
• Main Authors: Field, Nigel, Amirthalingam, Gayatri, Waight, Pauline, Andrews, Nick, Ladhani, Shamez N, van Hoek, Albert Jan, Maple, Peter A.C, Brown, Kevin E, Miller, Elizabeth
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 26-02-2014; Elsevier; Elsevier Limited; Elsevier Science
• Subjects: Adolescent; Adolescents; Allergy and Immunology; Antibodies, Viral - analysis; Applied microbiology; Biological and medical sciences; Chicken pox; Chickenpox; Chickenpox - epidemiology; Chickenpox - prevention & control; Chickenpox Vaccine - therapeutic use; Child; Children & youth; Confidence intervals; Cost-Benefit Analysis; Data analysis; England - epidemiology; Ethnicity; Families & family life; Fundamental and applied biological sciences. Psychology; Human viral diseases; Humans; Immunization; Immunization Programs; Immunoglobulin G - analysis; Infections; Infectious diseases; Medical History Taking; Medical sciences; Microbiology; Predictive Value of Tests; R&D; Reported history; Research & development; Schools; Teenagers; Vaccination programme; Vaccines; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects); Validity; Varicella; Viral diseases; Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye; England; United Kingdom; Great Britain; Europe; Western Europe; United Kingdom > UK; Varicella; Validity; Vaccination programme; Reported history; Chickenpox; Adolescent; Human; Infection; Skin disease; Targeting; Viral disease; Vaccination
• ISSN: 0264-410X; 1873-2518
• DOI: 10.1016/j.vaccine.2013.06.098

Highlights • Chickenpox history may enable cost-effective vaccination of susceptible individuals. • We tested the validity of reported chickenpox history in adolescents. • Vaccine would be wasted in most adolescents with a negative or uncertain history. • 6–9% of those with a positive chickenpox history would remain susceptible. • These data are needed to inform cost-effectiveness of proposed vaccine programmes.