Fatal Acute Exacerbation of Familial Interstitial Pneumonia Complicated with Dyskeratosis Congenita after Influenza Virus B Infection

• Published in: Internal Medicine Vol. 58; no. 18; pp. 2683 - 2687
• Main Authors: Tachiwada, Takashi, Oda, Keishi, Tahara, Masahiro, Sennari, Konomi, Nemoto, Kazuki, Noguchi, Shingo, Kawanami, Toshinori, Kido, Takashi, Yamaguchi, Hiroki, Yatera, Kazuhiro
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Society of Internal Medicine 15-09-2019; Japan Science and Technology Agency
• Subjects: acute exacerbation; Adult; Case Report; Disease Progression; Dyskeratosis; dyskeratosis congenita; Dyskeratosis Congenita - complications; familial interstitial pneumonia; Fatal Outcome; Humans; Infections; Influenza; Influenza B virus; Influenza, Human - complications; Influenza, Human - virology; Internal medicine; Lung Diseases, Interstitial - complications; Male; Medical personnel; Pneumonia; Viruses; acute exacerbation; dyskeratosis congenita; familial interstitial pneumonia
• ISSN: 0918-2918; 1349-7235
• DOI: 10.2169/internalmedicine.2413-18

Dyskeratosis congenita (DC) is occasionally complicated in patients with familial interstitial pneumonia (FIP). However, there have been no reports of FIP patients with DC that develop acute exacerbation (AE). We herein report a FIP patient with DC that showed AE of FIP after influenza virus B infection. Although DC is a rare disease in clinical practice, physicians should keep in mind that FIP combined with DC has the potential to cause AE.