Furin regulates both the activation of Pseudomonas exotoxin A and the Quantity of the toxin receptor expressed on target cells

• Published in: Infection and Immunity Vol. 64; no. 2; pp. 524 - 527
• Main Authors: MILI GU, GORDON, V. M, FITZGERALD, D. J. P, LEPPLA, S. H
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01-02-1996
• Subjects: ADP Ribose Transferases; Animals; Bacterial Toxins - metabolism; Bacteriology; Biological and medical sciences; Carrier Proteins; CHO Cells; Cricetinae; Exotoxins - metabolism; Fundamental and applied biological sciences. Psychology; Furin; Mice; Microbiology; Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains; Pseudomonas; Pseudomonas aeruginosa - pathogenicity; Pseudomonas aeruginosa Exotoxin A; Receptors, Cell Surface - analysis; Subtilisins - genetics; Subtilisins - physiology; Transfection; Virulence Factors; Pseudomonadales; α2-Macroglobulin; Serine endopeptidases; Enzyme; Host agent relation; Activation; Lipoprotein LDL; Toxin; Bacteria; Hydrolases; Pseudomonadaceae; Cleavage; Furin; Pseudomonas aeruginosa; Exotoxin; Proteinases; Biological receptor
• ISSN: 0019-9567; 1098-5522
• DOI: 10.1128/iai.64.2.524-527.1996

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