抗凝血杀鼠药的分析研究进展

抗凝血杀鼠药是目前广泛使用的一类慢性杀鼠药,与急性杀鼠药如毒鼠强相比,该类鼠药具有适口性好、不易被鼠拒食等特点,杀鼠效果显著。随着对该类药物研究的不断深入和新分析技术的使用,抗凝血杀鼠药的分析,尤其是难度较大的生物体内该类鼠药的分析研究取得了较大进展。本文就抗凝血杀鼠药分析的研究进展,结合各种研究成果做一综述,为法医毒物分析工作者提供参考。...

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Published in:复旦学报(医学版) Vol. 38; no. 4; pp. 361 - 366
Main Author: 严慧(综述) 沈敏(审校)
Format: Journal Article
Language:Chinese
Published: 司法部司法鉴定科学技术研究所法医毒物化学研究室-上海市法医学重点实验室,上海,200063 2011
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Summary:抗凝血杀鼠药是目前广泛使用的一类慢性杀鼠药,与急性杀鼠药如毒鼠强相比,该类鼠药具有适口性好、不易被鼠拒食等特点,杀鼠效果显著。随着对该类药物研究的不断深入和新分析技术的使用,抗凝血杀鼠药的分析,尤其是难度较大的生物体内该类鼠药的分析研究取得了较大进展。本文就抗凝血杀鼠药分析的研究进展,结合各种研究成果做一综述,为法医毒物分析工作者提供参考。
Bibliography:Anticoagulant rodenticides are chronic toxicants that are widely used in rodent control.They are highly effective rodenticides that kill rats and mice with high palatability and no resistance comparing with acute rodenticides such as tetramine.With the advancement of constant research on anticoagulant rodenticides and the use of new technology,progress achieves in the analysis of anticoagulant rodenticides,especially in biological samples.We summarized the progress on the analysis of anticoagulant rodenticides in order to provide references for analytical toxicologist.
anticoagulant; rodenticides; analysis; warfarin
YAN Hui,SHEN Min(Department of Forensic Toxicology,Institute of Forensic Science,Ministry of Justice-Shanghai Key Laboratory of Forensic Medicine,Shanghai 200063,China)
31-1885/R
ISSN:1672-8467
DOI:10.3969/j.issn.1672-8467.2011.04.018