Cortical thinness and volume differences associated with marijuana abuse in emerging adults

Highlights • Used Freesurfer to measure cortical thickness and volume in emerging adult marijuana (MJ) users. • Less cortical thickness in right hemisphere fusiform gyrus in MJ users vs. non-users. • Smaller thalamic volume in MJ users, vs. non-users, related to greater impulsivity. • RFG and thalam...

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Bibliographic Details
Published in:	Drug and alcohol dependence Vol. 155; pp. 275 - 283
Main Authors:	Mashhoon, Y, Sava, S, Sneider, J.T, Nickerson, L.D, Silveri, M.M
Format:	Journal Article
Language:	English
Published:	Ireland Elsevier Ireland Ltd 01-10-2015
Subjects:	Adolescent Adult Amygdala - pathology Atrophy - pathology Cannabis - adverse effects Case-Control Studies Cerebral Cortex - pathology Cognition Disorders - pathology Cortical thickness Female Fusiform gyrus Hippocampus - pathology Humans Impulsive Behavior Magnetic Resonance Imaging Male Marijuana Marijuana Abuse - pathology Marijuana Abuse - psychology Neuroimaging Psychiatry Thalamus Thalamus - pathology Volume Young Adult Young adults Marijuana Thalamus Fusiform gyrus Cortical thickness Young adults Volume
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Summary:	Highlights • Used Freesurfer to measure cortical thickness and volume in emerging adult marijuana (MJ) users. • Less cortical thickness in right hemisphere fusiform gyrus in MJ users vs. non-users. • Smaller thalamic volume in MJ users, vs. non-users, related to greater impulsivity. • RFG and thalamus may be connected through visual information processing pathway. • Altered rFG and thalamus integrity may impair visuoperceptual processing in MJ users.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Co-first authors
ISSN:	0376-8716 1879-0046
DOI:	10.1016/j.drugalcdep.2015.06.016