Association of Lifestyle and Body Composition on Risk Factors of Cardiometabolic Diseases and Biomarkers in Female Adolescents

• Published in: Mediators of inflammation Vol. 2020; no. 2020; pp. 1 - 12
• Main Authors: Priore, Silvia Eloiza, Peluzio, Maria do Carmo Gouveia, Faria, Fernanda Rocha, Júnior, Márcio Vidigal Miranda, Canabrava, Karina Lúcia Ribeiro, Bastos, Ronaldo Rocha, dos Santos Amorim, Paulo Roberto, Miranda, Valter Paulo Neves, do Carmo Castro Franceschini, Sylvia
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 2020; Hindawi; John Wiley & Sons, Inc; Hindawi Limited
• Subjects: Absorptiometry, Photon; Adolescent; Adolescents; Adult; Behavior; Biological markers; Biomarkers; Blood levels; Blood pressure; Blood Pressure - physiology; Body composition; Body Composition - physiology; Body fat; Body mass index; Body weight; C-reactive protein; Child development; Classification; Cross-Sectional Studies; Data collection; Dual energy X-ray absorptiometry; Exercise; Female; Females; High density lipoprotein; Humans; Inflammation; Insulin; Insulin resistance; Interleukin 6; Leptin; Life Style; Lifestyles; Lipoproteins; Obesity; Overweight; Overweight - physiopathology; Physical activity; Public schools; Risk Factors; Sample size; Sociodemographics; Software; Students; Studies; Teenage girls; Teenagers; Triglycerides; Tumor necrosis factor-TNF; Tumor necrosis factor-α; Uric acid; Young Adult; Brazil; United States > US
• ISSN: 0962-9351; 1466-1861
• DOI: 10.1155/2020/9170640

Background. Female adolescents are considered a risk group for cardiometabolic disease due to their lifestyle (LS). Objective. To evaluate the association between LS classes and body composition groups with cardiometabolic disease risk factors and pro- and anti-inflammatory biomarkers in female adolescents. Methods. This cross-sectional study was carried out with female adolescents aged 14 to 19 years, from Viçosa-MG, Brazil. Latent class analysis assessed LS classes. Kinanthropometric measurements were taken together with the body fat percentage (BF%), being analyzed by the Dual Energy X-ray Absorptiometry (DEXA) equipment. Blood pressure and biochemical parameters were analyzed in the Health Division of the Federal University of Viçosa. The pro- and anti-inflammatory biomarkers were analyzed using Luminex technology. Associations with biomarkers were estimated by multiple linear regression. Results. 405 female adolescents were evaluated. The majority, 82.57%, 72.90%, and 65.31%, were classified as inactive by the number of steps, with high screen and cell phone time, respectively. Furthermore, 41.55% did meet the minimum of 60 minutes of moderate-to-vigorous physical activity (MVPA) and 54.69% had high values of BF% (DEXA). The “Sedentary & Inactive LS” class together with the high levels of weight and BF% were associated with increased levels of blood pressure, lipid profile, and uric acid. It was also found that “Inactive & Sedentary LS”, high BF%, insulin resistance, and ultra-sensitive C-reactive protein were associated with the concentrations of proinflammatory biomarkers of tumor necrosis factor-α, interleukin-6, and leptin. Conclusion. We concluded that female adolescents with overweight/obese and high BF% presented higher values of anthropometric indicators, levels of blood pressure, concentration of uric acid and hs-CRP, and lower concentration of HDL. Inactive and Sedentary lifestyle of these girls, along with excess body fat, insulin resistance, and higher concentrations of hs-CRP were associated with the higher concentration proinflammatory markers.