Virology, Epidemiology, Pathogenesis, and Control of COVID-19

• Published in: Viruses Vol. 12; no. 4; p. 372
• Main Authors: Jin, Yuefei, Yang, Haiyan, Ji, Wangquan, Wu, Weidong, Chen, Shuaiyin, Zhang, Weiguo, Duan, Guangcai
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 27-03-2020; MDPI
• Subjects: Antiviral Agents - therapeutic use; Betacoronavirus; China; Clinical Laboratory Techniques - methods; Coronavirus Infections - diagnosis; Coronavirus Infections - epidemiology; Coronavirus Infections - physiopathology; Coronavirus Infections - prevention & control; Coronavirus Infections - therapy; Coronaviruses; COVID-19; COVID-19 Testing; COVID-19 Vaccines; Development and progression; Diagnosis; Disease control; Distribution; Drug development; Epidemiology; Genome, Viral; Humans; Medical virology; Pandemics; Pandemics - prevention & control; pathogenesis; Pneumonia, Viral - epidemiology; Pneumonia, Viral - physiopathology; Pneumonia, Viral - prevention & control; Pneumonia, Viral - therapy; Public Health; Review; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; therapeutics; Viral Vaccines; Virology; Viruses; China; COVID-19; epidemiology; pathogenesis; SARS-CoV-2; therapeutics
• ISSN: 1999-4915; 1999-4915
• DOI: 10.3390/v12040372

The outbreak of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) in China has been brought to global attention and declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Scientific advancements since the pandemic of severe acute respiratory syndrome (SARS) in 2002~2003 and Middle East respiratory syndrome (MERS) in 2012 have accelerated our understanding of the epidemiology and pathogenesis of SARS-CoV-2 and the development of therapeutics to treat viral infection. As no specific therapeutics and vaccines are available for disease control, the epidemic of COVID-19 is posing a great threat for global public health. To provide a comprehensive summary to public health authorities and potential readers worldwide, we detail the present understanding of COVID-19 and introduce the current state of development of measures in this review.