New Rule Proposed for Protein Degradation

Researchers at MIT have reported that the amino-terminal amino acid of a protein determines the protein's half-life. The information is of invaluable interest to molecular biologists who design and clone genes to make new pharmaceutical products.

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Bibliographic Details
Published in:	Science (American Association for the Advancement of Science) Vol. 234; no. 4773; pp. 151 - 152
Main Author:	Kolata, Gina
Format:	Journal Article
Language:	English
Published:	United States The American Association for the Advancement of Science 10-10-1986 American Association for the Advancement of Science
Subjects:	Amino acids Amino Acids - metabolism beta-Galactosidase - metabolism Biotechnology Cells, Cultured Dark matter Enzymes Genetic code Genetics Half lives Half-Life High temperature Innovations Microwaves Pharmaceutical industry Photons Protein biosynthesis Protein metabolism Protein research Protein synthesis Proteins Proteins - metabolism Research News Ubiquitins Ubiquitins - metabolism
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Description
Summary:	Researchers at MIT have reported that the amino-terminal amino acid of a protein determines the protein's half-life. The information is of invaluable interest to molecular biologists who design and clone genes to make new pharmaceutical products.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 SourceType-Other Sources-1 ObjectType-News-1 content type line 66
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.3018927