Tumor microenvironment in ovarian cancer peritoneal metastasis

Tumor microenvironment in ovarian cancer peritoneal metastasis

Ovarian cancer (OC) is one of the most common gynecological malignancies with high morbidity and mortality. The peritoneum is one of the most common metastatic sites in ovarian cancer, involving large amounts of ascites. However, its mechanism is unclear. The peritoneal microenvironment composed of...

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Bibliographic Details
Published in:Cancer cell international Vol. 23; no. 1; p. 11
Main Authors: Mei, Shuangshuang, Chen, Xing, Wang, Kai, Chen, Yuxin
Format: Journal Article
Language:English
Published: England BioMed Central 25-01-2023
BMC
Subjects:
Abdomen
Ascites
Cell adhesion & migration
Effusion
Hypotheses
Malignancy
Medical prognosis
Metastases
Metastasis
Molecular modelling
Morbidity
Ovarian cancer
Peritoneum
Review
Spheroids
Tumor microenvironment
Tumors
Tumor microenvironment
Metastasis
Ovarian cancer
Online Access:Get full text
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Summary:Ovarian cancer (OC) is one of the most common gynecological malignancies with high morbidity and mortality. The peritoneum is one of the most common metastatic sites in ovarian cancer, involving large amounts of ascites. However, its mechanism is unclear. The peritoneal microenvironment composed of peritoneal effusion and peritoneum creates favorable conditions for ovarian cancer progression and metastasis. Here, we reviewed the peritoneal metastasis patterns and molecular mechanisms of ovarian cancer, as well as major components of the peritoneal microenvironment, peritoneal effusion, and immune microenvironment, and investigated the relationship between the peritoneal microenvironment and ovarian cancer metastasis.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1475-2867
1475-2867
DOI:10.1186/s12935-023-02854-5