Preoperative T staging using CT colonography with multiplanar reconstruction for very low rectal cancer

• Published in: BMC cancer Vol. 17; no. 1; p. 764
• Main Authors: Shida, Dai, Iinuma, Gen, Komono, Akira, Ochiai, Hiroki, Tsukamoto, Shunsuke, Miyake, Mototaka, Kanemitsu, Yukihide
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 14-11-2017; BioMed Central; BMC
• Subjects: Cancer staging; Colorectal cancer; CT colonography; Diagnostic imaging; Lower rectal cancer; Multiplanar reconstruction (MPR); Preoperative T staging; Multiplanar reconstruction (MPR); Preoperative T staging; CT colonography; Lower rectal cancer
• ISSN: 1471-2407; 1471-2407
• DOI: 10.1186/s12885-017-3756-9

Preoperative T staging of lower rectal cancer is an important criterion for selecting intersphincteric resection (ISR) or abdominoperineal resection (APR) as well as selecting neoadjuvant therapy. The aim of this study was to evaluate the accuracy of preoperative T staging using CT colonography (CTC) with multiplanar reconstruction (MPR), in which with the newest workstation the images can be analyzed with a slice thickness of 0.5 mm.
Between 2011 and 2013, 45 consecutive patients with very low rectal adenocarcinoma underwent CTC with MPR. The accuracy of preoperative T staging using CTC with MPR was evaluated. The accuracy of preoperative T staging using MRI in the same patient population (34 of 45 patients) was also examined.
Overall accuracy of T staging was 89% (41/45) for CTC with MPR and 71% (24/34) for MRI. CTC with MPR was particularly sensitive for pT2 tumors (82%; 14/17), whereas MRI tended to overstage pT2 tumors and its sensitivity for pT2 was 53% (8/15).
CTC with MPR, with an arbitrary selection, could be aligned to the tumor axis and better demonstrated tumor margins consecutively including the deepest section of the tumor. The accuracy of T2 and T3 staging using CTC with MPR seemed to surpass that of MRI, suggesting a potential role of CTC with MPR in preoperative T staging for very low rectal cancer.