Patterns of sedentary time and cardiometabolic risk among Canadian adults

• Published in: Preventive medicine Vol. 65; pp. 23 - 27
• Main Authors: Carson, Valerie, Wong, Suzy L, Winkler, Elizabeth, Healy, Genevieve N, Colley, Rachel C, Tremblay, Mark S
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Inc 01-08-2014; Elsevier
• Subjects: Accelerometry; Adult; Aged; Biological and medical sciences; Biomarkers - blood; Blood pressure; Canada - epidemiology; Cardiovascular diseases; Cardiovascular Diseases - epidemiology; Cardiovascular Diseases - etiology; Cardiovascular Diseases - prevention & control; Cross-Sectional Studies; Environmental Monitoring - instrumentation; Environmental Monitoring - methods; Female; Glucose; Health; Health Surveys; Humans; Insulin; Insulin resistance; Insulin Resistance - physiology; Internal Medicine; Lipoproteins; Male; Medical sciences; Metabolic diseases; Metabolic Diseases - epidemiology; Metabolic Diseases - etiology; Metabolic Diseases - prevention & control; Middle Aged; Miscellaneous; Motor Activity; Other metabolic disorders; Prevention and actions; Public health. Hygiene; Public health. Hygiene-occupational medicine; Risk Assessment; Sedentary; Sedentary Lifestyle; Time Factors; Young Adult; Canada; North America; America; Sedentary lifestyle; Insulin resistance; Adult; Cardiovascular diseases; Endocrinopathy; Human; Pancreatic hormone; Metabolic diseases; Cardiovascular disease; Time; Metabolic syndrome; Coronary heart disease; Insulin; Target tissue resistance; Cardiovascular risk; Sedentary; Life style
• ISSN: 0091-7435; 1096-0260
• DOI: 10.1016/j.ypmed.2014.04.005

Abstract Objective The aim of this study is to examine the associations of total sedentary time and patterns of sedentary time with cardiometabolic biomarkers in a large representative sample of Canadian adults. Methods The study is based on 4935 adults aged 20–79 years, from the 2007/09 and 2009/11 Canadian Health Measures Survey. Total sedentary time, patterns of sedentary time (≥ 20 minute prolonged sedentary bouts, number of sedentary breaks), and moderate- to vigorous-intensity physical activity (MVPA) were accelerometer-derived. Waist circumference, systolic and diastolic blood pressure, high-density lipoprotein (HDL) cholesterol, and C-reactive protein were measured. Triglycerides, low-density lipoprotein (LDL) cholesterol, insulin, and glucose were also measured in a fasting sub-sample ( n = 2551). Results Total sedentary time and time in ≥ 20 minute prolonged sedentary bouts were associated with higher insulin and lower diastolic blood pressure levels ( P < 0.05). On average, each additional 10 breaks/day was associated with 0.83 (95%CI: 1.35, 0.31) cm lower waist circumference, 0.32 (0.62, 0.02) mm Hg lower systolic blood pressure, 0.01 (0.00, 0.02) mmol/l higher HDL-cholesterol, 3.72 (1.34, 6.13) % lower triglycerides, 0.57 (0.23, 0.92) % lower glucose, and 4.19 (1.80, 6.63) % lower insulin. Conclusion These findings in a large representative sample of Canadian adults indicate that breaking up sedentary time may be particularly important for cardiometabolic health.