Effectiveness of guided and unguided low-intensity internet interventions for adult alcohol misuse: a meta-analysis

• Published in: PloS one Vol. 9; no. 6; p. e99912
• Main Authors: Riper, Heleen, Blankers, Matthijs, Hadiwijaya, Hana, Cunningham, John, Clarke, Stella, Wiers, Reinout, Ebert, David, Cuijpers, Pim
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 17-06-2014; Public Library of Science (PLoS)
• Subjects: Addictions; Adults; Alcohol abuse; Alcohol Drinking - prevention & control; Alcohol use; Alcoholic beverages; Alcoholism - therapy; Biology and Life Sciences; Clinical psychology; Clinical trials; Cost analysis; Drinking behavior; Ethanol; Guidelines; Health Behavior; Humans; Internet; Intervention; Literature reviews; Medical screening; Medicine and Health Sciences; Mental depression; Mental health; Meta-analysis; Patient Compliance; Primary care; Public health; Randomized Controlled Trials as Topic; Risk assessment; Self help; Studies; Subgroups; Systematic review; Task forces; Treatment Outcome
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0099912

Alcohol misuse ranks within the top ten health conditions with the highest global burden of disease. Low-intensity, Internet interventions for curbing adult alcohol misuse have been shown effective. Few meta-analyses have been carried out, however, and they have involved small numbers of studies, lacked indicators of drinking within low risk guidelines, and examined the effectiveness of unguided self-help only. We therefore conducted a more thorough meta-analysis that included both guided and unguided interventions.
Systematic literature searches were performed up to September 2013. Primary outcome was the mean level of alcohol consumption and drinking within low risk guidelines for alcohol consumption at post-treatment.
We selected 16 randomised controlled trials (with 23 comparisons and 5,612 participants) for inclusion. Results, showed a small but significant overall effect size in favour of Internet interventions (g = 0.20, 95% CI: 0.13-0.27, p<.001). Participants in Internet interventions drunk on average 22 grams of ethanol less than controls and were significantly more likely to be adhering to low-risk drinking guidelines at post-treatment (RD 0.13, 95% CI: 0.09-0.17, p<.001). Subgroup analyses revealed no significant differences in potential moderators for the outcome of alcohol consumption, although there was a near-significant difference between comparisons with waitlist control and those with assessment-only or alcohol information control conditions (p = .056).
Internet interventions are effective in reducing adult alcohol consumption and inducing alcohol users to adhere to guidelines for low-risk drinking. This effect is small but from a public health point of view this may warrant large scale implementation at low cost of Internet interventions for adult alcohol misuse. Moderator analyses with sufficient power are, however, needed in order to assess the robustness of these overall results and to assess whether these interventions may impact on subgroups with different levels of success.