Inhaled nitric oxide therapy in adults : European expert recommendations

• Published in: Intensive care medicine Vol. 31; no. 8; pp. 1029 - 1041
• Main Authors: GERMANN, Peter, BRASCHI, Antonio, LITVAN, Hector, MACRAE, Duncan J, MAGGIORINI, Marco, MARCZIN, Nandor, MUELLER, Bernd, PAYEN, Didier, RANUCCI, Marco, SCHRANZ, Dietmar, ZIMMERMANN, Rainer, ULLRICH, Roman, DELLA ROCCA, Giorgio, DINH-XUAN, Anh Tuan, FALKE, Konrad, FROSTELL, Claes, GUSTAFSSON, Lars E, HERVE, Philippe, JOLLIET, Philippe, KAISERS, Udo
• Format: Journal Article
• Language: English
• Published: Heidelberg Springer 01-08-2005; Berlin Springer Nature B.V
• Subjects: Administration, Inhalation; Adult; Adults; Anesthesia; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Anesthesiology; Biological and medical sciences; Care and treatment; Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care; Europe; Health aspects; Heart Failure - therapy; Humans; Hypertension, Pulmonary - therapy; Intensive care; Intensive care medicine; Medical sciences; Medicin och hälsovetenskap; Medicine; Nitric oxide; Nitric Oxide - administration & dosage; Nitric Oxide - therapeutic use; Pharmacology. Drug treatments; Practice Guidelines as Topic; Pulmonary arteries; Pulmonary hypertension; Reperfusion Injury - therapy; Respiratory distress syndrome; Respiratory Distress Syndrome, Adult - therapy; Respiratory failure; Respiratory insufficiency; Respiratory system; Respiratory Therapy - methods; Europe; United Kingdom; Acute respiratory distress syndrome; Lung disease; Acute lung injury; Intensive care; Respiratory disease; Lung transplantation; Cardiovascular disease; Cardiac surgery; Pulmonary hypertension; Recommendation; Inhalation; Treatment; Nitric oxide; Surgery; Inhaled nitric oxide; Respiratory distress; Resuscitation
• ISSN: 0342-4642; 1432-1238
• DOI: 10.1007/s00134-005-2675-4

Inhaled nitric oxide (iNO) has been used for treatment of acute respiratory failure and pulmonary hypertension since 1991 in adult patients in the perioperative setting and in critical care.
This contribution assesses evidence for the use of iNO in this population as presented to a expert group jointly organised by the European Society of Intensive Care Medicine and the European Association of Cardiothoracic Anaesthesiologists.
Expert recommendations on the use of iNO in adults were agreed on following presentation of the evidence at the expert meeting held in June 2004.