CTLA-4 and PD-1 Receptors Inhibit T-Cell Activation by Distinct Mechanisms

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Published in:	Molecular and Cellular Biology Vol. 25; no. 21; pp. 9543 - 9553
Main Authors:	Parry, Richard V., Chemnitz, Jens M., Frauwirth, Kenneth A., Lanfranco, Anthony R., Braunstein, Inbal, Kobayashi, Sumire V., Linsley, Peter S., Thompson, Craig B., Riley, James L.
Format:	Journal Article
Language:	English
Published:	United States American Society for Microbiology 01-11-2005 Taylor & Francis
Subjects:	Antigens, CD Antigens, Differentiation - physiology Antigens, Surface - physiology Apoptosis Regulatory Proteins - physiology CD28 Antigens - metabolism CD3 Complex - metabolism CTLA-4 Antigen Enzyme Activation Gene Expression Regulation Humans In Vitro Techniques Lymphocyte Activation - physiology Okadaic Acid - pharmacology Oncogene Protein v-akt - metabolism Phosphatidylinositol 3-Kinases - antagonists & inhibitors Phosphatidylinositol 3-Kinases - metabolism Phosphatidylinositols - metabolism Phosphoprotein Phosphatases - antagonists & inhibitors Phosphoprotein Phosphatases - metabolism Phosphorylation Programmed Cell Death 1 Receptor Signal Transduction Signal Transduction - drug effects Signal Transduction - physiology T-Lymphocytes - drug effects T-Lymphocytes - metabolism T-Lymphocytes - physiology
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Summary:	Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue Spotlights in the Current Issue MCB About MCB Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy MCB RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0270-7306 Online ISSN: 1098-5549 Copyright © 2014 by the American Society for Microbiology. For an alternate route to MCB .asm.org, visit: MCB
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 These authors contributed equally to this work. Corresponding author. Mailing address: Abramson Family Cancer Research Institute, 556 BRB II/III, 421 Curie Blvd., University of Pennsylvania, Philadelphia, PA 19104. Phone: (215) 573-6792. Fax: (215) 573-8590. E-mail: rileyj@mail.med.upenn.edu.
ISSN:	0270-7306 1098-5549 1098-5549
DOI:	10.1128/MCB.25.21.9543-9553.2005