Activation of Src Kinase in Platelet-Derived Growth Factor-B-Dependent Tubular Regeneration after Acute Ischemic Renal Injury

We previously reported that the platelet-derived growth factor B-chain (PDGF-B)/PDGF receptor (PDGFR) axis is involved in tubular regeneration after ischemia/reperfusion injury of the kidney. In the present study, we examined the activation of Src tyrosine kinase, a crucially important signaling mol...

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Bibliographic Details
Published in:	The American journal of pathology Vol. 163; no. 1; pp. 277 - 286
Main Authors:	Takikita-Suzuki, Mikiko, Haneda, Masakazu, Sasahara, Masakiyo, Owada, M. Koji, Nakagawa, Takahiko, Isono, Motohide, Takikita, Shoichi, Koya, Daisuke, Ogasawara, Kazumasa, Kikkawa, Ryuichi
Format:	Journal Article
Language:	English
Published:	Bethesda, MD Elsevier Inc 01-07-2003 ASIP American Society for Investigative Pathology
Subjects:	Animals Biological and medical sciences Creatinine - blood Enzyme Activation Humans Immunohistochemistry Kidney Tubules - cytology Kidney Tubules - pathology Kidney Tubules - physiology Kidneys Male Medical sciences Nephrology. Urinary tract diseases Platelet Aggregation Inhibitors - metabolism Proliferating Cell Nuclear Antigen - metabolism Proto-Oncogene Proteins c-sis - metabolism Rats Rats, Sprague-Dawley Receptor, Platelet-Derived Growth Factor beta - metabolism Regeneration - physiology Regular Reperfusion Injury src-Family Kinases - metabolism Trapidil - metabolism Urinary system involvement in other diseases. Miscellaneous Kidney disease Urinary system disease Enzyme Transferases Acute Cardiovascular disease Activation Regeneration Experimental disease Platelet Ischemia Kinase Animal Platelet derived growth factor
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