Clinical significance and developmental changes of auditory-language-related gamma activity

• Published in: Clinical neurophysiology Vol. 124; no. 5; pp. 857 - 869
• Main Authors: Kojima, Katsuaki, Brown, Erik C, Rothermel, Robert, Carlson, Alanna, Fuerst, Darren, Matsuzaki, Naoyuki, Shah, Aashit, Atkinson, Marie, Basha, Maysaa, Mittal, Sandeep, Sood, Sandeep, Asano, Eishi
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ireland Ltd 01-05-2013
• Subjects: Adolescent; Adult; Brain - growth & development; Brain - physiopathology; Brain Mapping - methods; Child; Child, Preschool; Electroencephalography; Epilepsy - physiopathology; Epilepsy surgery; Event-related synchronization; Female; High-frequency oscillations (HFOs); Humans; Image Processing, Computer-Assisted; Intracranial EEG recording; Language; Male; Middle Aged; Neurology; Oncogenicity; Outcome; Ripples; Young Adult; High-frequency oscillations (HFOs); Event-related synchronization; Outcome; Ripples; Intracranial EEG recording; Epilepsy surgery; Oncogenicity
• ISSN: 1388-2457; 1872-8952
• DOI: 10.1016/j.clinph.2012.09.031

Highlights ► An auditory naming task elicited augmentation of gamma activity on intracranial ECoG in epileptic patients. ► The incidence of a post-operative language deficit requiring speech therapy was predicted by the number of resected sites with gamma-augmentation in the superior-temporal, inferior-frontal, dorsolateral-premotor, and inferior-Rolandic regions of the left hemisphere assumed to contain essential language function. ► Regardless of age, auditory-language-related gamma-augmentation most commonly involved the 80–100 Hz frequency band.